Rexulti *

Description

Rexulti / Brexpiprazole (generic name: brexpiprazole) is an oral drug prescribed for the treatment of schizophrenia in patients 13 years and older. It may also be prescribed to treat adults with major depressive disorder (MDD) as an adjunctive treatment to other antidepressants.

Brexpiprazole is a part of a therapeutic drug group called ‘atypical antipsychotic drugs’ that work by helping modulate the secretion of serotonin and dopamine from the receptors in the brain. This pharmacological profile provides benefits in mood stabilization and behavioral management.

Brexpiprazole also offers a treatment option for adults with schizophrenia and agitation associated with Alzheimer’s disease.

CautionTell your healthcare provider if you become pregnant or think you have become pregnant during treatment with Rexulti, since it can harm an unborn baby. Taking brexpiprazole during the third trimester of pregnancy may cause the baby to have abnormal muscle movements or withdrawal symptoms after birth.

Patients and their family members should be on alert for signs of worsening depression, suicidal thoughts, or other mood changes. Consult with a doctor if the person is showing any inclination towards self-harm.

DosageRexulti is administered orally, with or without food. Dosage varies based on the condition being treated:

MDD (for adjunctive treatment): A starting dose of 0.5 mg to 1 mg once daily, with a target dose of 2 mg/day.Schizophrenia: A starting dose of 1 mg once daily, with a target dose of 2 to 4 mg/day.Agitation in Alzheimer’s Disease: A starting dose of 0.5 mg once daily, titrated to a target dose of 2 mg/day.Dosage adjustments can be be made by a doctor, based on your response and tolerability. Even if there is an improvement in your condition, do not stop the treatment without first talking to the doctor.

Do not divide the tablet. The tablets do not have a score/dividing line and therefore the tablets cannot be split into equal doses.

StorageIf in any doubt, consult our blog on safe medicine management. Store below 30ºC / 82ºF in the original packaging, away from light and moisture.

Common Questions About Rexulti / BrexpiprazoleAre there any off-label uses for Rexulti?A doctor may prescribe the drug off-label for anxiety other than in Alzheimer’s patients. In dosages of up to 4 mg per day, it has been shown to also treat bipolar disorder in adults.

What are the unusual urges of Rexulti?According to the comapny’s website, some people taking the drug have experienced strong unusual urges that cannot be controlled. These included  compulsive gambling, sexual urges, shopping, and binge eating.

Does brexpiprazole help with anger?Clinical studies have indicated that brexpiprazole may help reduce irritability and anger symptoms in patients with major depressive disorder. Its work in managing agitation associated with Alzheimer’s disease further supports its role in addressing such behavioral disturbances.

Does brexpiprazole cause weight gain?Yes, weight gain is a common side effect of brexpiprazole. In clinical trials, patients experienced an average weight gain of approximately 3.1 kg (6.8 lbs) over one year. Regular monitoring of weight is recommended.